Obesity memory!
Some environmental exposures are brief, but the body keeps receipts via epigenetic and metabolic long-lasting marks.
What goes on your plate can determine how the immune system responds, remembers, and misfires.
Obesity, which was once viewed solely as a consequence of excess energy storage, is now increasingly associated with a state of epigenetic reprogramming.
Obesity memory may undermine long-term weight-loss success by driving weight regain despite improvements in metabolic health.
Recent work has placed lipid metabolism at the forefront of obesity memory.
https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(26)00250-X
